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KMID : 0363320020230020174
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Journal of Korean Oriental Internal Medicine
2002 Volume.23 No. 2 p.174 ~ p.180
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The Effect of the Extract of Angelica gigas on the Serum Alcohol and Acetaldehyde Concentration in Rats
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Jung Woo-Sang
Song Jae-Chul
Park Jung-Mi
Kim Sang-Woo
Lee Hee-Sul
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Abstract
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Objectives : Our study was designed to assess whether the extract of Angelica gigas can lower serum alcohol and acetaldehyde concentration in drunken rats.
Methods : We divided Sprague-Dawley male rats into 3 groups of a Vehicle control, Positive control and Angelica gigas group. Serum alcohol and acetaldehyde levels were checked at baseline, 0.5, 1, 2 and 4 hours after drinking ethanol. Independent t-test was performed to assess the difference of the serum concentrations between the Angelica gigas induced group and the control group.
Results : Angelica gigas lowered the serum acetaldehyde concentration. However, it did not lower alcohol concentration effect.
Conclusions : We assume that Angelica gigas could be effective for alcohol induced hangover.
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KEYWORD
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Angelica gigas, Alcohol, Acetaldehyde, Hangover
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